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OCR: enzymes twisting could prevent the strands from separatins cleanly in preparation for replication In many ways, then pyranosyl RNA seems better suited for replication than RNA itself. simple means for synthesizing ribonucleotides containing a six-member sugar ring were found case could be made that this form of RNA may have preceded the more familiar form of the molecule In quite different approach Peter E Nielsen of the University Copenhagen has used computer assisted model building to design polymer that combines protein -like backbone with nucleic acid bases for side chains As is true of RNA one strand 0f this polymer or peptide nucleic acid (PNA), can combine stably with a complementary strand; this result implies that as is true of standard RNA, peptide RNA may be able to serve asa te ...